Endocrine Abstracts

This study was designed to investigate effects of raloxifene treatment on serum interleukin (IL)-4 and transforming growth factor-beta (TGFbeta)1 concentrations in healthy postmenopausal women. The study was approved by the local ethics committee. Thirty five women were enrolled into this study and randomly divided in two groups. While 16 women were included in raloxifene group, control group was comprised of remaining 19 women. The study group continuously received 60 mg ralo...

Nebivolol is a recently developed beta(1)-selective adrenergic receptor antagonist with proposed nitric oxide mediated vasodilating properties. Effect of nebivolol on vascular smooth muscle has been attributed to estrogen receptor-mediated vascular responsiveness. Although it is known that nitric oxide has relaxing effect on myometrium, there is no report whether nebivolol application affect myometrial contractility. Therefore, we have investigated the effect of nebivolol on r...

Objective: The relationship between metabolic syndrome (MS) and hypogonadism has always been investigated in study groups confounded with aging, obesity or chronic metabolic disorders. So far there has been no data about the presence of MS in young hypogonadal patients. Also there is controversial data about the metabolic effects of testosteron replacement therapy. We investigated the frequency of MS in treatment naïve, young men with congenital hypogonadal hypogonadism (...